Polypoidal Choroidal Vasculopathy

PurposeTo develop consensus terminology in the setting of polypoidal choroidal vasculopathy (PCV) and to validate a set diagnostic criteria not requiring indocyanine green angiography (ICGA) for differentiating PCV from typical neovascular age-related macular degeneration (nAMD) based on combination OCT color fundus photography findings.DesignEvaluation test results.ParticipantsPanel retina specialists.MethodsAs part Asia-Pacific Ocular Imaging Society, an international group experts surveyed discussed published literature regarding current nomenclature lesion components PCV, proposed updated that reflects our latest understanding imaging histologic reports. The workgroup evaluated features images photographs may distinguish it nAMD assessed performance individual combinations these non-ICGA features, aiming propose new does require use ICGA. final recommendation was validated 80 eyes 2 additional cohorts.Main Outcome MeasuresConsensus system non–ICGA-based differentiate nAMD.ResultsThe recommended terms branching network key PCV. For diagnosis 3 OCT-based major (sub–retinal pigment epithelium [RPE] ring-like lesion, en face complex RPE elevation, sharp-peaked PED) achieved area under receiver operating characteristic curve 0.90. Validation this scheme separate subset accuracy 82%.ConclusionsWe better nature lesions is consensus. A practical applied easily spectral-domain results can be used diagnosing with high clinical settings which ICGA performed routinely. To findings. Evaluation results. Panel specialists. As cohorts. Consensus nAMD. 82%. We